The reception history of the French Revolution in France and England is well documented among Anglophone scholars; however, the debate over the Revolution in Germany is much less well known. Fichte's Contribution played an important role in this debate. Presented here for the first time in English, Fichte's work provides a distinctive synthesis of Locke's "possessive individualism," Rousseau's general will, and Kant's moral philosophy. This eclectic blend results in an unusual rights theory that at times veers close to a form (...) of anarchism. Written in 1792–93, just before Fichte moved to Jena to develop his philosophical system in a series of works—above all the Wissenschaftslehre of 1794—the Contribution provides invaluable insight into Fichte's early development. In addition, Fichte's work predates much of Kant's political philosophy, and can shed light on the rich dialogue in German political thought in the 1790s. (shrink)

I am now sitting in La Antigua, Guatemala. It's 6:00 a.m. Ancient church bells compete with their clanging. Some with a clear ringing, others of dead metal. For centuries this tiny town of some 20 square blocks was the very center of Christianity in the "new" world. Its philosophy was brought to this place, lock, stock, and barrel. And, from here it was funneled south to Peru and north to Mexico. Not a philosophy of "liberation." Just ask the Maya (...) who remain. (shrink)

Plasminogen activator inhibitor‐1 (PAI‐1) is a physiological inhibitor of urokinase (uPA), a serine protease known to promote cell migration and invasion. Intuitively, increased levels of PAI‐1 should be beneficial in downregulating uPA activity, particularly in cancer. By contrast, in vivo, increased levels of PAI‐1 are associated with a poor prognosis in breast cancer. This phenomenon is termed the “PAI‐1 paradox”. Many factors are responsible for the upregulation of PAI‐1 in the tumor microenvironment. We hypothesize that there is a breast cancer (...) predisposition to a more aggressive stage when PAI‐1 is upregulated as a consequence of Metabolic Syndrome (MetS). MetS exerts a detrimental effect on the breast tumor microenvironment that supports cancer invasion. People with MetS have an increased risk of coronary heart disease, stroke, peripheral vascular disease and hyperinsulinemia. Recently, MetS has also been identified as a risk factor for breast cancer. We hypothesize the existence of the “PAI‐1 cycle”. Sustained by MetS, adipocytokines alter PAI‐1 expression to promote angiogenesis, tumor‐cell migration and procoagulant microparticle formation from endothelial cells, which generates thrombin and further propagates PAI‐1 synthesis. All of these factors culminate in a chemotherapy‐resistant breast tumor microenvironment. The PAI‐1 cycle may partly explain the PAI‐1 paradox. In this hypothesis paper, we will discuss further how MetS upregulates PAI‐1 and how an increased level of PAI‐1 can be linked to a poor prognosis. BioEssays 29:1029–1038, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

Locke was born in Wrington, Somerset, on 29 August 1632. After the Civil War he was sent to Westminster School, and in 1652 to Christ Church, Oxford. A feature of the university in Locke's early years was growing interest in the natural sciences, fostered by, amongst others, Robert Boyle, John Wilkins, and Robert Hooke. After graduating, Locke was much attracted to the work of these men, and soon he was engaged in medical research with Robert Boyle. He remained in (...) Oxford until 1667, when a chance meeting with Anthony Ashley Cooper, later Lord Shaftesbury, led to his joining Shaftesbury's London household, which from then on became Locke's usual residence, and where he acted as Shaftesbury's personal physician, conducted research with Thomas Sydenham. and became a Fellow of the Royal Society. (shrink)

The extended Church-Turing thesis posits that any computable function can be calculated efficiently by a probabilistic Turing machine. If this thesis held true, the global effort to build quantum computers might ultimately be unnecessary. The thesis would however be strongly contradicted by a physical device that efficiently performs a task believed to be intractable for classical computers. BosonSampling - the sampling from a distribution of n photons undergoing some linear-optical process - is a recently developed, and experimentally accessible example (...) of such a task [1]. (shrink)

Before Edward Gibbon began his history of the Christian empire, he ended the first volume of the “Decline and Fall” with two chapters on the rise of Christianity before Constantine. These were believed to deny or ignore its character as revelation. It was also pointed out that this purpose was irrelevant to the history he had set out to write. The church historians he read focussed on the interactions between the Christian gospel and Hellenic philosophy. Gibbon, however, chose to (...) emphasize the Christian rejection of cultic polytheism, and gave a Humean account of the early Christians as enthusiasts. Five years elapsed between the first and second volumes of his history. By the latter date his reputation as an unbeliever was established, and has since received more attention than the history he wrote. (shrink)

A.G. van Aarde and historical Jesus research. A.G. van Aarde’s contribution to historical Jesus research is mainly expressed in his book Fatherless in Galilee: Jesus as Child of God. The book was the result of five years of Jesus research. Van Aarde is an ordained minister of the Netherdutch Reformed Church of Africa. Since the book’s publication in 2001, the NRCA has experienced an immense dispute regarding the book in particular but also regarding the subject of historical Jesus research (...) in general. This dispute has publicly escalated since 2010. It has often centred on Van Aarde’s notion of Jesus’ fatherlessness. This article will focus on said book in order to ascertain what is meant by the concept ‘the fatherless Jesus’. This is done to illustrate that Van Aarde’s research, as it converges in the scrutinised publication, remains of relevance to the NRCA. (shrink)

Contains three lectures on vaguely related topics. John Cogley outlines the sources of religious conflict in the United States. Holding that the First Amendment was intended not to discourage religion but to promote religious liberty, he develops principles for the solution of problems of Church-State relations. Paul Weiss discusses the more theoretical problem of the relationship of natural and supernatural law. Natural law derives from a common good relative to a particular group, and is strictly utilitarian. Reference to a (...) supernatural or divinely given good is necessary to adjudicate between and order the differing and possibly conflicting common goods of different groups, and to provide for ethical laws that transcend utilitarian considerations. John Wu sees the main prerequisite of a future world democracy as a meeting of the insights and cultures of the East and West.--A. F. G. (shrink)

In this essay, the author both reviews Scott Sowerby's book Making Toleration: The Repealers and the Glorious Revolution and makes a late contribution to, or comment on, the Common Knowledge symposium “Fuzzy Studies”. Sowerby opposes the “Whig interpretation” that James II was attempting to reinstate Stuart “popery and arbitrary government” and instead presents James II's policies as aimed at liberation of the Stuart monarchy from the borough, county, and clerical elites that had brought it back to power and regarded restoration (...) of the Church of England as their instrument and identity. The king thus had his own reasons for upholding the liberty of conscience, and so James II can be found using the language of a skeptical Enlightenment, while at the same time affirming the absoluteness of his authority and incurring the suspicion of popery. How “toleration” of Catholics and dissenters came about in Britain must be told by narrating the “hard” histories of various state structures, but there is a larger and “softer” history of Enlightenment to be extracted from that of the European ancien régime, in whose history and downfall “British history” has a part that can be narrated in both “hard” and “soft” terms. The recent revisionist accounts of James II — of which Sowerby's is said in this review to be among the best — offer the king a new role at that regime's beginnings. This review concludes by arguing that the pursuit of history as it has come to be practiced is among the “softest” modes of explanation — since it consists of the unending and unlimited pursuit of the contexts in which actions, words, and processes have been situated and need to be studied — and that the more there are of these, the more meanings the actions may bear and the fewer reasons there are for the use of Occam's razor. “The notion of ‘fuzziness’ ” does not disturb historians, as it does scholars in some other disciplines, since historians have at their disposal an established contextualist “means of navigating it.”. (shrink)

G. W. F. Hegel and Friedrich Nietzsche are often considered the philosophical antipodes of the nineteenth century. In _Infinite Autonomy_, Jeffrey Church draws on the thinking of both Hegel and Nietzsche to assess the modern Western defense of individuality—to consider whether we were right to reject the ancient model of community above the individual. The theoretical and practical implications of this project are important, because the proper defense of the individual allows for the survival of modern liberal institutions in (...) the face of non-Western critics who value communal goals at the expense of individual rights. By drawing from Hegelian and Nietzschean ideas of autonomy, Church finds a third way for the individual—what he calls the “historical individual,” which goes beyond the disagreements of the ancients and the moderns while nonetheless incorporating their distinctive contributions. (shrink)

Interpretations of the conflict between Galileo and the Roman Curia are many and various. A few commentators profess to see no great issues at stake, and are inclined to dismiss the Trial of 1633 as merely the outcome of personal jealousies and local intrigues. Others see the Trial as damning evidence for the Church’s rooted hostility to scientific enquiry. Others again find no evidence of a conflict between the Church and science, and see the Trial as one more (...) instance of a routine administrative authority frowning on the would-be innovator: something which is likely to happen in any field where there is an official ‘establishment’. (shrink)

Church has recently proposed a solution of the paradox of analysis as propounded by Langford in which Church makes use of Frege's distinction between the sense (Sinn) of a name and its denotation (Bedeutung). The main purpose of the present note. is to show that a, version of the paradox may be presented which is not directly solved by Church in his review but which, in turn, may be solved by using; another distinction of Frege-that between the (...) ordinary (gewihnlich) and the oblique (ungerade) use of a name. The second part of the note will be concerned with the relative merits of this second distinction of Frege and Quine's related distinction between purely designative occurrences of a name and occurrences which are not purely designative; they will be compared merely with respect to their effectiveness in removing or solving the paradox of analysis. (shrink)

The central issues of regnum versus sacerdotium have been obscured by a concentration on personalities and a murder in a cathedral. Cantor is also concerned with personalities, but in this thorough study of church-state relations in Anglo-Norman England, he goes behind the legend and ably demonstrates that the controversies which were dramatized in blood in 1170 had already been settled by politico-ecclesiastical negotiations more than half-a-century earlier. The main interest of the study is in Cantor's discussion of St. Anselm (...) as an aging ecclesiastical statesman trying to avoid the extremes of that "fanatical high Gregorian" Paschal II, while insisting on the ending of lay investiture despite Henry I's opposition.--H. G. K. (shrink)

A reduction algebra is defined as a set with a collection of partial unary functions (called reduction operators). Motivated by the lambda calculus, the Church-Rosser property is defined for a reduction algebra and a characterization is given for those reduction algebras satisfying CRP and having a measure respecting the reductions. The characterization is used to give (with 20/20 hindsight) a more direct proof of the strong normalization theorem for the impredicative second order intuitionistic propositional calculus.

Prior to the outbreak of the coronavirus disease 2019 pandemic, the churches in Nigeria contended with Bokoharam insurgency which mainly affected the churches in Northern Nigeria. However, COVID-19 affected various churches in all the nooks and crannies of the country. It brought about obvious changes in numerous practices of churches in Nigeria. Long-standing traditions of churches such as solemnisation of Holy Matrimony, Holy Communion, baptism, prayer and sharing of peace have been modified or suspended. Whilst this article appreciates the efforts (...) of the federal and state governments, it investigates the implications of COVID-19 outbreak on traditional religious practices of churches in Nigeria. It also examines the responses of churches towards controlling the pandemic. The phenomenological method is used to analyse the data collected from both primary and secondary sources. Findings from this work indicate that COVID-19 outbreak is a challenge to the purpose of the institution 'church'.CONTRIBUTION: The article investigated and examined the changes which churches made in their doctrine and liturgy with respect to the outbreak of COVID-19 in Nigeria. It discovered that many traditions of the church have been modified or suspended as a way of curtailing the spread of the virus. (shrink)

Recent work in cognitive science of religion (CSR) is beginning to converge on a very interesting thesis—that, given the ordinary features of human minds operating in typical human environments, we are naturally disposed to believe in the existence of gods, among other religious ideas (e.g., seeAtran [2002], Barrett [2004; 2012], Bering [2011], Boyer [2001], Guthrie [1993], McCauley [2011], Pyysiäinen [2004; 2009]). In this paper, we explore whether such a discovery ultimately helps or hurts the atheist position—whether, for example, it lends (...) credence to atheism by explaining away religious belief or whether it actually strengthens some already powerful arguments against atheism in the relevant philosophical literature.We argue that the recent discoveries of CSR hurt, not help, the atheist position—that CSR, if anything, should not give atheists epistemic assurance. (shrink)